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Artificial womb keeps animal fetus alive for 12 days

VnExpressVnExpress02/07/2023


Spain Experts are working to develop an artificial womb for premature babies after successful animal trials.

Artificial womb keeps animal fetus alive for 12 days

Spanish researchers develop artificial womb. Video : Reuters

In testing, the prototype artificial placenta recreated the protective environment with a transparent container made of biocompatible materials, Reuters reported on June 30. Inside it, the fetus's lungs, intestines and brain could continue to develop. The container is connected to an amniotic fluid circulation system to keep the fetus isolated from external stimuli but still accessible for ultrasound monitoring and control.

Babies born after just six months in the womb or less are considered extremely premature, with a high risk of death or disability. Around 900,000 such babies died worldwide in 2019, according to the World Health Organization (WHO).

"We are trying to develop a system that allows the fetus to be kept outside the mother's body but still in fetal conditions: continuing to breathe through the umbilical cord, eating through the umbilical cord, surrounded by a liquid at a constant temperature," said project leader Eduard Gratacos, who leads a team of 35 people from the BCNatal medical research center and Fundacion La Caixa.

The team has conducted preclinical studies on lambs and kept fetuses alive for 12 days. They also plan to test the technology on pigs before proposing human trials in the next few years.

“The project is very complex, it involves many different medical disciplines and requires engineers from many fields. It is a huge challenge, it will be extremely complicated to trick nature and make this possible,” said Gratacos.

Kelly Werner, an associate professor of pediatrics at Columbia University, said the Spanish team's promising results must be rigorously tested in human clinical trials to assess safety and side effects. "This is an exciting development, but the artificial placenta is not intended to replace the natural placenta. Despite advances like this, we should still make every effort to support maternal health and reduce risk factors for preterm birth," Werner said.

Thu Thao (According to Reuters )



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