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What happens when we drink coffee on an empty stomach?

Drinking coffee on an empty stomach can cause different reactions depending on each person’s constitution and health. Some people are not affected at all, but many people are prone to experiencing very unpleasant symptoms.

Báo Lào CaiBáo Lào Cai11/09/2025

1. Common side effects of drinking coffee on an empty stomach

Coffee is one of the most popular drinks with many benefits including increased alertness, improved athletic performance and enhanced brain function. Many people can safely drink coffee on an empty stomach, but others may experience severe gastrointestinal discomfort and other symptoms.

Drinking coffee on an empty stomach increases stomach acid and heartburn

Drinking coffee stimulates increased acid production in the stomach, and drinking it on an empty stomach causes the stomach to produce more acid. Excess acid in the stomach can irritate the stomach lining and cause heartburn.

When acid flows back up into the esophagus, it causes a burning sensation in the chest known as heartburn or reflux. Caffeine also relaxes the lower esophageal sphincter, a ring of muscle between the esophagus (food pipe) and the stomach, increasing reflux.

Therefore, people with a history of heartburn and gastroesophageal reflux should be careful to avoid drinking coffee on an empty stomach. Before drinking coffee, you should have a light meal or drink it after eating.

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Drinking coffee on an empty stomach increases stomach acid and heartburn.

Faster absorption of caffeine and increased side effects

Caffeine is a natural stimulant, and consuming too much can lead to restlessness, rapid heartbeat, and anxiety. It can also cause headaches and increase blood pressure.

Drinking coffee on an empty stomach causes our bodies to absorb caffeine faster and increases these symptoms. Drinking coffee after a meal helps slow down the absorption process and reduces the risk of experiencing caffeine side effects.

Impact on the intestines

Caffeine is a stimulant for bowel movements. For those who are sensitive, drinking coffee on an empty stomach can cause bloating, nausea, abdominal pain, and diarrhea. People with irritable bowel syndrome often experience gastrointestinal discomfort or diarrhea after drinking coffee.

Increased sense of tension

The caffeine in coffee stimulates the release of cortisol, often called the stress hormone. Cortisol regulates metabolism and blood pressure. Elevated cortisol levels increase the risk of anxiety, irritability, and sleep problems.

When drinking coffee on an empty stomach, this effect can be stronger, leading to feelings of restlessness, anxiety, and a rapid heartbeat. However, the increase in cortisol production from caffeine is small and not associated with serious health problems.

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Drinking coffee after meals helps slow down absorption and reduce the risk of caffeine side effects.

2. How long does it take for caffeine to wear off?

Caffeine typically reaches peak blood levels about an hour after ingestion. While this varies from person to person, the effects of caffeine are usually noticeable within four to six hours of consumption, and it can take longer for it to completely leave the body.

According to the US Food and Drug Administration (FDA), for most adults, consuming 400 mg of caffeine, equivalent to 4-5 cups of coffee per day, is not usually associated with negative effects. However, there is a wide variation in how sensitive people are to the effects of caffeine and how quickly they eliminate it from their bodies.

Caffeine has a half-life of about four to six hours. This means that within about six hours of a person consuming caffeine, at least half of the caffeine is still in the body.

Therefore, we need to pay attention to this to adjust the appropriate drinking time, especially for those who are sensitive to caffeine and have experienced unpleasant symptoms when drinking coffee on an empty stomach.

In short, consuming too much caffeine or drinking coffee on an empty stomach can lead to negative side effects because each person has different tolerance and sensitivity to caffeine. Therefore, people who are sensitive to caffeine, people with poor health and stomach problems, reflux, insomnia, high blood pressure, etc. should be careful when drinking coffee.

It is best to consult your doctor or nutritionist for advice appropriate to your health condition.

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Source: https://baolaocai.vn/dieu-gi-xay-ra-khi-chung-ta-uong-ca-phe-luc-doi-post881760.html


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